Publications 2005

Aichberger, K. J., Mayerhofer, M., Krauth, M. T., Skvara, H., Florian, S., Sonneck, K., Akgul, C., Derdak, S., Pickl, W. F., Wacheck, V., Selzer, E., Monia, B. P., Moriggl, R., Valent, P. & Sillaber, C. Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides. Blood 105, 3303-3311, doi:10.1182/blood-2004-02-0749 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/15626746

Aichberger, K. J., Mayerhofer, M., Krauth, M. T., Vales, A., Kondo, R., Derdak, S., Pickl, W. F., Selzer, E., Deininger, M., Druker, B. J., Sillaber, C., Esterbauer, H. & Valent, P. Low-level expression of proapoptotic Bcl-2-interacting mediator in leukemic cells in patients with chronic myeloid leukemia: role of BCR/ABL, characterization of underlying signaling pathways, and reexpression by novel pharmacologic compounds. Cancer Res 65, 9436-9444, doi:10.1158/0008-5472.CAN-05-0972 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/16230407

Bluml, S., Kirchberger, S., Bochkov, V. N., Kronke, G., Stuhlmeier, K., Majdic, O., Zlabinger, G. J., Knapp, W., Binder, B. R., Stockl, J. & Leitinger, N. Oxidized phospholipids negatively regulate dendritic cell maturation induced by TLRs and CD40. J Immunol 175, 501-508, doi:10.4049/jimmunol.175.1.501 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/15972685

Choremi-Papadopoulou, H., Faure, G. C., Grunnet, N., Madden, M., Malenica, B., Misbah, S. A., Theodorsson, E. & Zlabinger, G. J. Position statement: training programme in immunology of the European Board of UEMS Medical Biopathology. Immunol Lett 96, 305-310, doi:10.1016/j.imlet.2004.09.009 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/15585339

Feik, N., Bilic, I., Tinhofer, J., Unger, B., Littman, D. R. & Ellmeier, W. Functional and molecular analysis of the double-positive stage-specific CD8 enhancer E8III during thymocyte development. J Immunol 174, 1513-1524, doi:10.4049/jimmunol.174.3.1513 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/15661911

Geyeregger, R., Zeyda, M., Zlabinger, G. J., Waldhausl, W. & Stulnig, T. M. Polyunsaturated fatty acids interfere with formation of the immunological synapse. J Leukoc Biol 77, 680-688, doi:10.1189/jlb.1104687 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/15703198

Kirchberger, S., Majdic, O., Steinberger, P., Bluml, S., Pfistershammer, K., Zlabinger, G., Deszcz, L., Kuechler, E., Knapp, W. & Stockl, J. Human rhinoviruses inhibit the accessory function of dendritic cells by inducing sialoadhesin and B7-H1 expression. J Immunol 175, 1145-1152, doi:10.4049/jimmunol.175.2.1145 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/16002716

Kirsch, B. M., Zeyda, M., Stuhlmeier, K., Grisar, J., Smolen, J. S., Watschinger, B., Stulnig, T. M., Horl, W. H., Zlabinger, G. J. & Saemann, M. D. The active metabolite of leflunomide, A77 1726, interferes with dendritic cell function. Arthritis Res Ther 7, R694-703, doi:10.1186/ar1727 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/15899055

Marquez, M. E., Ellmeier, W., Sanchez-Guajardo, V., Freitas, A. A., Acuto, O. & Di Bartolo, V. CD8 T cell sensory adaptation dependent on TCR avidity for self-antigens. J Immunol 175, 7388-7397, doi:10.4049/jimmunol.175.11.7388 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/16301646

Mayerhofer, M., Aichberger, K. J., Florian, S., Krauth, M. T., Hauswirth, A. W., Derdak, S., Sperr, W. R., Esterbauer, H., Wagner, O., Marosi, C., Pickl, W. F., Deininger, M., Weisberg, E., Druker, B. J., Griffin, J. D., Sillaber, C. & Valent, P. Identification of mTOR as a novel bifunctional target in chronic myeloid leukemia: dissection of growth-inhibitory and VEGF-suppressive effects of rapamycin in leukemic cells. FASEB J 19, 960-962, doi:10.1096/fj.04-1973fje (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/15784722

Saemann, M. D., Weichhart, T., Horl, W. H. & Zlabinger, G. J. Tamm-Horsfall protein: a multilayered defence molecule against urinary tract infection. Eur J Clin Invest 35, 227-235, doi:10.1111/j.1365-2362.2005.01483.x (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/15816991

Saemann, M. D., Weichhart, T., Zeyda, M., Staffler, G., Schunn, M., Stuhlmeier, K. M., Sobanov, Y., Stulnig, T. M., Akira, S., von Gabain, A., von Ahsen, U., Horl, W. H. & Zlabinger, G. J. Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a Toll-like receptor-4-dependent mechanism. J Clin Invest 115, 468-475, doi:10.1172/JCI22720 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/15650774

Sarafova, S. D., Erman, B., Yu, Q., Van Laethem, F., Guinter, T., Sharrow, S. O., Feigenbaum, L., Wildt, K. F., Ellmeier, W. & Singer, A. Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity. Immunity 23, 75-87, doi:10.1016/j.immuni.2005.05.011 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/16039581

Weichhart, T., Zlabinger, G. J. & Saemann, M. D. The multiple functions of Tamm-Horsfall protein in human health and disease: a mystery clears up. Wien Klin Wochenschr 117, 316-322, doi:10.1007/s00508-005-0353-8 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/15989109

Wohrl, S., Loewe, R., Pickl, W. F., Stingl, G. & Wagner, S. N. EMPACT syndrome. J Dtsch Dermatol Ges 3, 39-43, doi:10.1046/j.1439-0353.2005.04737.x (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/16353748

Zeyda, M., Kirsch, B. M., Geyeregger, R., Stuhlmeier, K. M., Zlabinger, G. J., Horl, W. H., Saemann, M. D. & Stulnig, T. M. Inhibition of human dendritic cell maturation and function by the novel immunosuppressant FK778. Transplantation 80, 1105-1111, doi:10.1097/01.tp.0000178301.19732.a1 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/16278593

Zeyda, M., Poglitsch, M., Geyeregger, R., Smolen, J. S., Zlabinger, G. J., Horl, W. H., Waldhausl, W., Stulnig, T. M. & Saemann, M. D. Disruption of the interaction of T cells with antigen-presenting cells by the active leflunomide metabolite teriflunomide: involvement of impaired integrin activation and immunologic synapse formation. Arthritis Rheum 52, 2730-2739, doi:10.1002/art.21255 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/16142756

Zeyda, M., Saemann, M. D., Stuhlmeier, K. M., Mascher, D. G., Nowotny, P. N., Zlabinger, G. J., Waldhausl, W. & Stulnig, T. M. Polyunsaturated fatty acids block dendritic cell activation and function independently of NF-kappaB activation. J Biol Chem 280, 14293-14301, doi:10.1074/jbc.M410000200 (2005).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/15684433