Publications 2007

Aichberger, K. J., Mayerhofer, M., Gleixner, K. V., Krauth, M. T., Gruze, A., Pickl, W. F., Wacheck, V., Selzer, E., Mullauer, L., Agis, H., Sillaber, C. & Valent, P. Identification of MCL1 as a novel target in neoplastic mast cells in systemic mastocytosis: inhibition of mast cell survival by MCL1 antisense oligonucleotides and synergism with PKC412. Blood 109, 3031-3041, doi:10.1182/blood-2006-07-032714 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17110460

Attarbaschi, A., Mann, G., Schumich, A., Konig, M., Pickl, W. F., Haas, O. A., Gadner, H. & Dworzak, M. N. CD44 deficiency is a consistent finding in childhood Burkitt's lymphoma and leukemia. Leukemia 21, 1110-1113, doi:10.1038/sj.leu.2404608 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17330102 

Bilic, I. & Ellmeier, W. The role of BTB domain-containing zinc finger proteins in T cell development and function. Immunol Lett 108, 1-9, doi:10.1016/j.imlet.2006.09.007 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17084908 

Geyeregger, R., Zeyda, M., Bauer, W., Kriehuber, E., Saemann, M. D., Zlabinger, G. J., Maurer, D. & Stulnig, T. M. Liver X receptors regulate dendritic cell phenotype and function through blocked induction of the actin-bundling protein fascin. Blood 109, 4288-4295, doi:10.1182/blood-2006-08-043422 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17255360

Gleixner, K. V., Mayerhofer, M., Sonneck, K., Gruze, A., Samorapoompichit, P., Baumgartner, C., Lee, F. Y., Aichberger, K. J., Manley, P. W., Fabbro, D., Pickl, W. F., Sillaber, C. & Valent, P. Synergistic growth-inhibitory effects of two tyrosine kinase inhibitors, dasatinib and PKC412, on neoplastic mast cells expressing the D816V-mutated oncogenic variant of KIT. Haematologica 92, 1451-1459, doi:10.3324/haematol.11339 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18024392 

Gleixner, K. V., Rebuzzi, L., Mayerhofer, M., Gruze, A., Hadzijusufovic, E., Sonneck, K., Vales, A., Kneidinger, M., Samorapoompichit, P., Thaiwong, T., Pickl, W. F., Yuzbasiyan-Gurkan, V., Sillaber, C., Willmann, M. & Valent, P. Synergistic antiproliferative effects of KIT tyrosine kinase inhibitors on neoplastic canine mast cells. Exp Hematol 35, 1510-1521, doi:10.1016/j.exphem.2007.06.005 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17681669 

Hantschel, O., Rix, U., Schmidt, U., Burckstummer, T., Kneidinger, M., Schutze, G., Colinge, J., Bennett, K. L., Ellmeier, W., Valent, P. & Superti-Furga, G. The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib. Proc Natl Acad Sci U S A 104, 13283-13288, doi:10.1073/pnas.0702654104 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17684099

Hochegger, K., Eller, P., Huber, J. M., Bernhard, D., Mayer, G., Zlabinger, G. J. & Rosenkranz, A. R. Expression of granzyme A in human polymorphonuclear neutrophils. Immunology 121, 166-173, doi:10.1111/j.1365-2567.2006.02551.x (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17244155

Kirchberger, S., Majdic, O. & Stockl, J. Modulation of the immune system by human rhinoviruses. Int Arch Allergy Immunol 142, 1-10, doi:10.1159/000095993 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17016053

Koesters, C., Unger, B., Bilic, I., Schmidt, U., Bluml, S., Lichtenberger, B., Schreiber, M., Stockl, J. & Ellmeier, W. Regulation of dendritic cell differentiation and subset distribution by the zinc finger protein CTCF. Immunol Lett 109, 165-174, doi:10.1016/j.imlet.2007.02.006 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17368809 

Kondo, R., Gleixner, K. V., Mayerhofer, M., Vales, A., Gruze, A., Samorapoompichit, P., Greish, K., Krauth, M. T., Aichberger, K. J., Pickl, W. F., Esterbauer, H., Sillaber, C., Maeda, H. & Valent, P. Identification of heat shock protein 32 (Hsp32) as a novel survival factor and therapeutic target in neoplastic mast cells. Blood 110, 661-669, doi:10.1182/blood-2006-10-054411 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17420286

Kueng, H. J., Leb, V. M., Haiderer, D., Raposo, G., Thery, C., Derdak, S. V., Schmetterer, K. G., Neunkirchner, A., Sillaber, C., Seed, B. & Pickl, W. F. General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines. J Virol 81, 8666-8676, doi:10.1128/JVI.00682-07 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17537846

Jorgl, A., Platzer, B., Taschner, S., Heinz, L. X., Hocher, B., Reisner, P. M., Gobel, F., Strobl, H. Human Langerhans-cell activation triggered in vitro by conditionally expressed MKK6 is counterregulated by the downstream effector RelB.  Blood. 109(1):185-93. doi: 10.1182/blood-2006-05-022954. (2007).
Abstract: https://pubmed.ncbi.nlm.nih.gov/16960152/

Mechtcheriakova, D., Wlachos, A., Sobanov, J., Bornancin, F., Zlabinger, G., Baumruker, T. & Billich, A. FTY720-phosphate is dephosphorylated by lipid phosphate phosphatase 3. FEBS Lett 581, 3063-3068, doi:10.1016/j.febslet.2007.05.069 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17555747 

Mechtcheriakova, D., Wlachos, A., Sobanov, J., Kopp, T., Reuschel, R., Bornancin, F., Cai, R., Zemann, B., Urtz, N., Stingl, G., Zlabinger, G., Woisetschlager, M., Baumruker, T. & Billich, A. Sphingosine 1-phosphate phosphatase 2 is induced during inflammatory responses. Cell Signal 19, 748-760, doi:10.1016/j.cellsig.2006.09.004 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17113265 

Park, J. H., Adoro, S., Lucas, P. J., Sarafova, S. D., Alag, A. S., Doan, L. L., Erman, B., Liu, X., Ellmeier, W., Bosselut, R., Feigenbaum, L. & Singer, A. 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR. Nat Immunol 8, 1049-1059, doi:10.1038/ni1512 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17873878

Rebuzzi, L., Willmann, M., Sonneck, K., Gleixner, K. V., Florian, S., Kondo, R., Mayerhofer, M., Vales, A., Gruze, A., Pickl, W. F., Thalhammer, J. G. & Valent, P. Detection of vascular endothelial growth factor (VEGF) and VEGF receptors Flt-1 and KDR in canine mastocytoma cells. Vet Immunol Immunopathol 115, 320-333, doi:10.1016/j.vetimm.2006.11.009 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17196258

Stefanova, T., Nikolova, N., Michailova, A., Mitov, I., Iancov, I., Zlabinger, G. J. & Neychev, H. Enhanced resistance to Salmonella enterica serovar Typhimurium infection in mice after coumarin treatment. Microbes Infect 9, 7-14, doi:10.1016/j.micinf.2006.10.001 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17196418

Taschner, S., Koesters, C., Platzer, B., Jorgl, A., Ellmeier, W., Benesch, T. & Strobl, H. Down-regulation of RXRalpha expression is essential for neutrophil development from granulocyte/monocyte progenitors. Blood 109, 971-979, doi:10.1182/blood-2006-04-020552 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17018855

Zeyda, M., Farmer, D., Todoric, J., Aszmann, O., Speiser, M., Gyori, G., Zlabinger, G. J. & Stulnig, T. M. Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production. Int J Obes (Lond) 31, 1420-1428, doi:10.1038/sj.ijo.0803632 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17593905 

Zeyda, M., Geyeregger, R., Poglitsch, M., Weichhart, T., Zlabinger, G. J., Koyasu, S., Horl, W. H., Stulnig, T. M., Watschinger, B. & Saemann, M. D. Impairment of T cell interactions with antigen-presenting cells by immunosuppressive drugs reveals involvement of calcineurin and NF-kappaB in immunological synapse formation. J Leukoc Biol 81, 319-327, doi:10.1189/jlb.0606378 (2007).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17038582