Publications 2008

Baumgartner, C., Gleixner, K. V., Peter, B., Ferenc, V., Gruze, A., Remsing Rix, L. L., Bennett, K. L., Samorapoompichit, P., Lee, F. Y., Pickl, W. F., Esterbauer, H., Sillaber, C., Superti-Furga, G. & Valent, P. Dasatinib inhibits the growth and survival of neoplastic human eosinophils (EOL-1) through targeting of FIP1L1-PDGFRalpha. Exp Hematol 36, 1244-1253, doi:10.1016/j.exphem.2008.04.017 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18619723 

Bluml, S., Rosc, B., Lorincz, A., Seyerl, M., Kirchberger, S., Oskolkova, O., Bochkov, V. N., Majdic, O., Ligeti, E. & Stockl, J. The oxidation state of phospholipids controls the oxidative burst in neutrophil granulocytes. J Immunol 181, 4347-4353, doi:10.4049/jimmunol.181.6.4347 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18768893 

Flicker, S., Steinberger, P., Eibensteiner, P. B., Lebecque, S., Kraft, D. & Valenta, R. Molecular characterization of a human immunoglobulin G4 antibody specific for the major birch pollen allergen, Bet v 1. Clin Exp Allergy 38, 365-373, doi:10.1111/j.1365-2222.2007.02883.x (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18070167 

Greinix, H. T., Pohlreich, D., Kouba, M., Kormoczi, U., Lohmann, I., Feldmann, K., Zielinski, C. & Pickl, W. F. Elevated numbers of immature/transitional CD21- B lymphocytes and deficiency of memory CD27+ B cells identify patients with active chronic graft-versus-host disease. Biol Blood Marrow Transplant 14, 208-219, doi:10.1016/j.bbmt.2007.10.009 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18215781

Hadzijusufovic, E., Rebuzzi, L., Gleixner, K. V., Ferenc, V., Peter, B., Kondo, R., Gruze, A., Kneidinger, M., Krauth, M. T., Mayerhofer, M., Samorapoompichit, P., Greish, K., Iyer, A. K., Pickl, W. F., Maeda, H., Willmann, M. & Valent, P. Targeting of heat-shock protein 32/heme oxygenase-1 in canine mastocytoma cells is associated with reduced growth and induction of apoptosis. Exp Hematol 36, 1461-1470, doi:10.1016/j.exphem.2008.06.002 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18723263 

Holzl, M. A., Hofer, J., Steinberger, P., Pfistershammer, K. & Zlabinger, G. J. Host antimicrobial proteins as endogenous immunomodulators. Immunol Lett 119, 4-11, doi:10.1016/j.imlet.2008.05.003 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18573543

Huber, J., Kiefer, F. W., Zeyda, M., Ludvik, B., Silberhumer, G. R., Prager, G., Zlabinger, G. J. & Stulnig, T. M. CC chemokine and CC chemokine receptor profiles in visceral and subcutaneous adipose tissue are altered in human obesity. J Clin Endocrinol Metab 93, 3215-3221, doi:10.1210/jc.2007-2630 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18492752 

Jahn-Schmid, B., Sirven, P., Leb, V., Pickl, W. F., Fischer, G. F., Gadermaier, G., Egger, M., Ebner, C., Ferreira, F., Maillere, B. & Bohle, B. Characterization of HLA class II/peptide-TCR interactions of the immunodominant T cell epitope in Art v 1, the major mugwort pollen allergen. J Immunol 181, 3636-3642, doi:10.4049/jimmunol.181.5.3636 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18714038

Kirchberger, S., Majdic, O., Bluml, S., Schrauf, C., Leitner, J., Gerner, C., Paster, W., Gundacker, N., Sibilia, M. & Stockl, J. The cytoplasmic tail of CD45 is released from activated phagocytes and can act as an inhibitory messenger for T cells. Blood 112, 1240-1248, doi:10.1182/blood-2008-02-138131 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18511809 

Kneidinger, M., Schmidt, U., Rix, U., Gleixner, K. V., Vales, A., Baumgartner, C., Lupinek, C., Weghofer, M., Bennett, K. L., Herrmann, H., Schebesta, A., Thomas, W. R., Vrtala, S., Valenta, R., Lee, F. Y., Ellmeier, W., Superti-Furga, G. & Valent, P. The effects of dasatinib on IgE receptor-dependent activation and histamine release in human basophils. Blood 111, 3097-3107, doi:10.1182/blood-2007-08-104372 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18180381 

Kober, J., Leitner, J., Klauser, C., Woitek, R., Majdic, O., Stockl, J., Herndler-Brandstetter, D., Grubeck-Loebenstein, B., Reipert, B. M., Pickl, W. F., Pfistershammer, K. & Steinberger, P. The capacity of the TNF family members 4-1BBL, OX40L, CD70, GITRL, CD30L and LIGHT to costimulate human T cells. Eur J Immunol 38, 2678-2688, doi:10.1002/eji.200838250 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18825741

Leb, V. M., Jahn-Schmid, B., Schmetterer, K. G., Kueng, H. J., Haiderer, D., Neunkirchner, A., Fischer, G. F., Nissler, K., Hartl, A., Thalhamer, J., Bohle, B., Seed, B. & Pickl, W. F. Molecular and functional analysis of the antigen receptor of Art v 1-specific helper T lymphocytes. J Allergy Clin Immunol 121, 64-71, doi:10.1016/j.jaci.2007.10.006 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18037161 

Mayerhofer, M., Gleixner, K. V., Mayerhofer, J., Hoermann, G., Jaeger, E., Aichberger, K. J., Ott, R. G., Greish, K., Nakamura, H., Derdak, S., Samorapoompichit, P., Pickl, W. F., Sexl, V., Esterbauer, H., Schwarzinger, I., Sillaber, C., Maeda, H. & Valent, P. Targeting of heat shock protein 32 (Hsp32)/heme oxygenase-1 (HO-1) in leukemic cells in chronic myeloid leukemia: a novel approach to overcome resistance against imatinib. Blood 111, 2200-2210, doi:10.1182/blood-2006-11-055723 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18024796 

Melcher, M., Unger, B., Schmidt, U., Rajantie, I. A., Alitalo, K. & Ellmeier, W. Essential roles for the Tec family kinases Tec and Btk in M-CSF receptor signaling pathways that regulate macrophage survival. J Immunol 180, 8048-8056, doi:10.4049/jimmunol.180.12.8048 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18523268 

Pfistershammer, K., Klauser, C., Leitner, J., Stockl, J., Majdic, O., Weichhart, T., Sobanov, Y., Bochkov, V., Saemann, M., Zlabinger, G. & Steinberger, P. Identification of the scavenger receptors SREC-I, Cla-1 (SR-BI), and SR-AI as cellular receptors for Tamm-Horsfall protein. J Leukoc Biol 83, 131-138, doi:10.1189/jlb.0407231 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17928461

Raberger, J., Boucheron, N., Sakaguchi, S., Penninger, J. M. & Ellmeier, W. Impaired T-cell development in the absence of Vav1 and Itk. Eur J Immunol 38, 3530-3542, doi:10.1002/eji.200838388 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/19009524 

Raberger, J., Schebesta, A., Sakaguchi, S., Boucheron, N., Blomberg, K. E., Berglof, A., Kolbe, T., Smith, C. I., Rulicke, T. & Ellmeier, W. The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells. Proc Natl Acad Sci U S A 105, 17919-17924, doi:10.1073/pnas.0805733105 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/19004789 

Seyerl, M., Bluml, S., Kirchberger, S., Bochkov, V. N., Oskolkova, O., Majdic, O. & Stockl, J. Oxidized phospholipids induce anergy in human peripheral blood T cells. Eur J Immunol 38, 778-787, doi:10.1002/eji.200737619 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18266300

Shinohara, M., Koga, T., Okamoto, K., Sakaguchi, S., Arai, K., Yasuda, H., Takai, T., Kodama, T., Morio, T., Geha, R. S., Kitamura, D., Kurosaki, T., Ellmeier, W. & Takayanagi, H. Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals. Cell 132, 794-806, doi:10.1016/j.cell.2007.12.037 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18329366 

Sillaber, C., Mayerhofer, M., Bohm, A., Vales, A., Gruze, A., Aichberger, K. J., Esterbauer, H., Pfeilstocker, M., Sperr, W. R., Pickl, W. F., Haas, O. A. & Valent, P. Evaluation of antileukaemic effects of rapamycin in patients with imatinib-resistant chronic myeloid leukaemia. Eur J Clin Invest 38, 43-52, doi:10.1111/j.1365-2362.2007.01892.x (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18173550 

Strehl, S., Nebral, K., Konig, M., Harbott, J., Strobl, H., Ratei, R., Struski, S., Bielorai, B., Lessard, M., Zimmermann, M., Haas, O. A., Izraeli, S. ETV6-NCOA2: a novel fusion gene in acute leukemia associated with coexpression of T-lymphoid and myeloid markers and frequent NOTCH1 mutations. Clin Cancer Res. 10.1158/1078-0432.CCR-07-4022. (2008).
Abstract: https://pubmed.ncbi.nlm.nih.gov/18281529/

Zebedin, E., Simma, O., Schuster, C., Putz, E. M., Fajmann, S., Warsch, W., Eckelhart, E., Stoiber, D., Weisz, E., Schmid, J. A., Pickl, W. F., Baumgartner, C., Valent, P., Piekorz, R. P., Freissmuth, M. & Sexl, V. Leukemic challenge unmasks a requirement for PI3Kdelta in NK cell-mediated tumor surveillance. Blood 112, 4655-4664, doi:10.1182/blood-2008-02-139105 (2008).
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18684865